Sex-specific susceptibility to cocaine in rats with a history of prenatal stress
Across species, maternal stress during prenatal life (prenatal stress [PS]) increases the expression of health complications in the developing offspring. While numerous reports indicate that male rats with a history of PS are vulnerable to psychiatric disease-like symptoms and drugs of abuse, comparable studies with females have been more limited. Here, the effects of PS […]
Housing conditions affect self-administration of anxiolytic by laboratory mice
Tests of emotionality conducted outside the home-cage show that rodents from standard laboratory housing are more anxious than animals from enriched housing; however, it is not known if this also indicates increased anxiety within the home-cage. We used a novel method, recording the self-administration of a psychoactive anxiolytic, to examine home-cage anxiety levels of laboratory […]