Long-lasting, selective, anxiogenic effects of feline predator stress in mice

Lasting increases in anxiety-like behavior (ALB) are produced by brief exposure of rats to a cat [Adamec RE, Shallow T, Lasting effects on rodent anxiety of a single exposure to a cat, Physiol. Behav., 54 (1993) 101–109.]. Mice also respond defensively to natural predator stimuli. Moreover, chronic exposure of mice to rat odor has immediate […]

Neural plasticity, neuropeptides and anxiety in animals — implications for understanding and treating affective disorder following traumatic stress in humans

Exposure of rats to cats (predator stress) lastingly increases rodent anxiety-like behavior (ALB) in the elevated plus-maze. Previous work shows that lasting changes in ALB following predator stress depend on NMDA and CCKB receptors. In this paper we describe the effects of differing degrees of predator exposure on behavior. Effects depend on the behavioral measure. […]