Analysis of endogenous cortisol concentrations in the hair of rhesus macaques

Short-term changes in activity of the hypothalamic–pituitary–adrenocortical (HPA) system are routinely assessed by measuring glucocorticoid or metabolite concentrations in plasma, saliva, urine, or feces. However, there are no current methods for determining long-term (i.e., weeks or months) activity of this system. Herein, we describe the development and validation of a simple procedure for measuring cortisol […]