Can disbudding of calves (one versus four weeks of age) induce chronic pain?

Background Calf disbudding is a welfare-relevant invasive husbandry procedure. While it is widely recognized that disbudding elicits acute pain, its chronic consequences are currently unknown. Objectives Primary aim of this study was to investigate whether disbudding leads to chronic pain in calves; secondary aim was to evaluate the influence of age at disbudding (1 week versus […]

Selective disturbance of pain sensitivity after social isolation

The effects of social isolation or NMDA-receptor antagonists on pain sensitivity have repeatedly been described. However, the mechanisms underlying the alterations of pain perception in these models still remain a matter of debate. Thus, we aimed to determine the long-lasting effects of subchronic ketamine treatment and social isolation on the C- and Aδ-fiber-mediated nociception. Wistar […]

The influence of lesion type on the duration of hyperalgesia associated with hindlimb lameness in dairy cattle

The nociceptive thresholds of 42 sound dairy cattle were compared with 53 animals displaying hind-claw lameness. All animals in the study were lameness scored and nociceptive threshold tested. Each animal then received a routine claw trim while the lame cattle also had the cause of lameness determined and treated. Those cattle found to have a […]