Predation threat exerts specific effects on rat maternal behaviour and anxiety-related behaviour of male and female offspring
Differences in the rate of maternal behaviours received by rodent offspring are associated with differential programming of molecular and behavioural components of anxiety and stress-related functions. To determine the degree to which maternal behaviours are sensitive to environmental conditions, Long–Evans rat dams were exposed to the odour of a predator (cat) at two different time […]
Environmental enrichment exerts anxiolytic effects in the Indian field mouse (Mus booduga)
Environmental enrichment (EE) is known to have behavioral and physiological anxiolytic effects in several animal models. However, it is as yet unclear how EE modulates behavior of wild animals and the underlying molecular mechanisms. The adult male field mouse Mus booduga (n = 42) captured at agricultural field, were housed in non-enriched standard condition (SC) […]
Effects of chronic mild stress on behavioral and neurobiological parameters — Role of glucocorticoid
Major depression is thought to originate from maladaptation to adverse events, particularly when impairments occur in mood-related brain regions. Hypothalamus–pituitary–adrenal (HPA) axis is one of the major systems involved in physiological stress response. HPA axis dysfunction and high glucocorticoid concentrations play an important role in the pathogenesis of depression. In addition, astrocytic disability and dysfunction […]