Pharmacological therapy with a combination of alprazolam and fluoxetine and use of the trace element lithium gluconate for treating anxiety disorders and aggression in dogs

This research studied 2 different treatments, lithium gluconate and a combination of alprazolam and fluoxetine, with the aim of assessing their efficacy for treating anxiety disorders in dogs. One hundred thirty-five dogs took part in the study, divided into 2 diagnostic categories: anxious dogs with aggression and anxious dogs with no aggression. The animals in […]

Serotonin modulates anxiety-like behaviors during withdrawal from adolescent anabolic–androgenic steroid exposure in Syrian hamsters

From the U.S. to Europe and Australia anabolic steroid abuse remains high in the adolescent population. This is concerning given that anabolic steroid use is associated with a higher incidence of pathological anxiety that often appears during withdrawal from use. This study uses pubertal Syrian hamsters (Mesocricetus auratus) to investigate the hypothesis that adolescent anabolic/androgenic […]

The smell of “anxiety”: Behavioral modulation by experimental anosmia in zebrafish

Olfaction is strongly involved in the regulation of fish behavior, including reproductive, defensive, social and migration behaviors. In fish, anosmia (the lack of olfaction) can be induced experimentally, impairing their ability to respond to various olfactory stimuli. Here, we examine the effects of experimental lidocaine-induced anosmia on anxiety-like behavior and whole-body cortisol levels in adult […]