Exploration and risk assessment: a comparative study of male house mice (Mus musculus musculus) and two laboratory strains
The ability to gather information and assess risks in novel environments is crucial for survival and fitness in the wild. Our aim was to characterise behavioural strategies of exploration and risk assessment in novel environments and to investigate in what respects wild house mice differ from domesticated mice. A total of 39 adult male mice […]
Sex and diet affect the behavioral response of rats to chronic mild stressors
To investigate the interaction between sex, stressors, and dietary choice in rats, a preferred diet under the influence of chronic mild stressors was empirically determined to consist of soybeans and cookies in addition to lab chow. This preferred mixed diet was then tested for its influence on several behavioral tests at the end of prolonged […]
Behavioral profiles and stress-induced corticosteroid secretion in male Wistar rats subjected to short and prolonged periods of maternal separation
Early life experiences are important for the development of neurobiobehavioral mechanisms and subsequent establishment of mental functions. In experimental animals, early life experiences can be studied using the maternal separation model. Maternal separation has been described to induce neurobiological changes and thus affect brain function, mental state and behavior. We have established a protocol in […]
Behavioral specificity of non-genomic glucocorticoid effects in rats: Effects on risk assessment in the elevated plus-maze and the open-field
The rapid effects of glucocorticoids on various behaviors suggest that these hormones play a role in rapidly coping with challenging situations. The variety of behaviors affected in different situations raise, however, questions regarding the specificity and roles of glucocorticoids in controlling behavior. To clarify this issue, we assessed the rapid behavioral effects of glucocorticoids in […]
Signs of attenuated depression-like behavior in vasopressin deficient Brattleboro rats
Vasopressin, a peptide hormone functioning also as a neurotransmitter, neuromodulator and regulator of the stress response is considered to be one of the factors related to the development and course of depression. In the present study, we have tested the hypothesis that congenital deficit of vasopressin in Brattleboro rats leads to attenuated depression-like behavior in […]
The effect of three different items of cage furniture on the behaviour of male C57BL/6J mice in the plus-maze test
The aim of this study was to assess the effects of specific regimens of enrichment on the behaviour of C57BL/6J mice in the elevated plus-maze test (EPM). A total of 192 male C57BL/6J mice were allocated randomly to 32 cages. Three different items of cage furniture (CF) made of aspen — a mouse corner, nestbox […]
Neonatal maternal separation in male rats increases intestinal permeability and affects behavior after chronic social stress
Prolonged maternal separation in rats has several effects on health and behavior. Here we investigated how maternal separation might interact with social stress in adulthood on behavior and gastrointenstinal permeability. The effects of either daily 180 min long term pup-dam separation (LMS) during the stress hyporesponsive period or daily 10 min brief maternal separation (BMS) […]
Correlates between ear postures and emotional reactivity in a wild type mouse species
Facial expressions have been extensively used to assess emotions in humans and thus could be extended to other species that also display facial movements. In mice both painful and fearful situations have been associated with particular shifts in facial expressions. Like other species, mice frequently show a great inter-individual variability when exposed to emotional situations, […]