Training to reliably obtain blood and urine samples from a diabetic chimpanzee (Pan troglodytes)
Abstract 10.1002/(SICI)1098-2361(1996)15:63.3.CO;2-P Positive reinforcement training techniques were used to gain the cooperation of a socially housed, 3-year-old, insulin-dependent diabetic chimpanzee (Pan troglodytes) in obtaining blood and urine samples for monitoring of glucose levels. A urine collection device, adaptable to many types of caging, allowed collection of urine from the diabetic subject as well as other […]
Chronic stress, energy balance and adiposity in female rats
Stress preferentially increases the consumption of high fat foods in women, suggesting the interaction of these two factors may disproportionately predispose women toward excess weight gain. In the present study, female rats were exposed to a chronic high fat or chow diet and were exposed to 4 weeks of chronic variable stress (CVS) or served […]
Group size, cage shelf level, and emotionality in non-obese diabetic mice: Impact on onset and incidence of IDDM
We hypothesized that differential housing, shown to influence emotionality and health in infectious and neoplastic disease, would influence onset/incidence of diabetes in an autoimmune animal model of insulin-dependent diabetes mellitus (IDDM). Non-obese diabetic mice were assigned to same-sex groups of one, five, or eight animals/cage, counterbalanced across shelf level by sex and group. During weekly […]